The Business of Contact Lenses - Scorecard - MDSpire

The Business of Contact Lenses

  • By

  • CLARKE D. NEWMAN, OD, FAAO

  • April 1, 2025

  • 5 min

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Clinical Scorecard: Corneal Cross-Linking (CXL) in Specialty Contact Lens Practice

At a Glance

CategoryDetail
ConditionKeratoconus and corneal ectasia post-refractive surgery
Key MechanismsCorneal cross-linking with riboflavin to prevent progressive corneal distortion
Target PopulationPatients aged 14 years or older with documented progression of keratoconus or ectasia
Care SettingOphthalmology and specialty contact lens practice with referral to CXL-capable surgeons

Key Highlights

  • CXL is FDA-approved and considered standard of care since 2015 for keratoconus and ectatic diseases.
  • Medical necessity criteria include documented progression via keratometry or refraction changes within 24 months.
  • Contraindications include corneal scarring, severe ocular surface disease, prior herpetic infection, and insufficient corneal thickness.

Guideline-Based Recommendations

Diagnosis

  • Confirm keratoconus diagnosis based on keratometry and corneal topography.
  • Document progression defined as ≥1 D increase in steepest keratometry or manifest cylinder, or ≥0.50 D increase in spherical equivalent within 24 months.
  • Ensure corrected distance visual acuity worse than 20/20 with proper correction.

Management

  • Refer patients meeting criteria for CXL to qualified surgeons or perform CXL if trained.
  • Verify corneal thickness is ≥300 microns (some guidelines recommend ≥400 microns) before procedure.
  • Rule out contraindications such as corneal scarring, severe ocular surface disease, prior or current herpetic infection.

Monitoring & Follow-up

  • Monitor keratometry and refraction changes over time to assess progression.
  • Maintain documentation to support medical necessity for insurance coverage.

Risks

  • Potential for delayed epithelial healing especially in patients with prior chemical injury or systemic disease.
  • Contraindications include corneal scarring and active ocular infections.

Patient & Prescribing Data

Patients with progressive keratoconus or ectasia aged 14 years and older

Insurance coverage may vary; patients should verify benefits due to possible coverage gaps despite medical necessity.

Clinical Best Practices

  • Establish firm diagnosis with topography before referral.
  • Provide detailed progression documentation to surgeons to support insurance approval.
  • Educate patients about potential insurance coverage limitations and encourage verification with their payors.

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