Comparison of the association and discriminatory ability of CVAI, LAP, CI, and AVI for type 2 diabetes in Chinese adults aged ≥ 50 years: a sex-specific analysis - Scorecard - MDSpire

Comparison of the association and discriminatory ability of CVAI, LAP, CI, and AVI for type 2 diabetes in Chinese adults aged ≥ 50 years: a sex-specific analysis

  • By

  • Liu Zhang

  • Liying Wen

  • Guimei Chen

  • Jingwen Puyang

  • Zizhou Cheng

  • Yu Zhu

  • Weiwei Chang

  • May 20, 2026

  • 0 min

Share

Clinical Scorecard: Evaluation of the Relationships and Discriminatory Power of CVAI, LAP, CI, and AVI in Predicting Type 2 Diabetes Among Chinese Adults Aged 50 and Older: A Gender-Specific Study

At a Glance

CategoryDetail
ConditionType 2 Diabetes Mellitus (T2DM)
Key MechanismsVisceral adiposity indices (CVAI, LAP, CI, AVI) associated with T2DM risk.
Target PopulationChinese adults aged 50 years and older.
Care SettingCommunity-based case-control study.

Key Highlights

  • All four indices (CVAI, LAP, CI, AVI) positively associated with prevalent T2DM.
  • CVAI showed the highest discriminatory ability (AUC 0.634) in the overall population.
  • Sex differences observed: CVAI and CI stronger in males; LAP stronger in females.
  • Prospective studies needed to validate findings.

Guideline-Based Recommendations

Diagnosis

  • Use visceral adiposity indices for assessing T2DM risk in older adults.

Management

  • Consider sex-specific differences in adiposity indices when evaluating T2DM risk.

Monitoring & Follow-up

  • Regular assessment of visceral fat indices in older populations.

Risks

  • Increased T2DM risk associated with higher visceral adiposity.

Patient & Prescribing Data

Adults aged 50 years and older in China.

Focus on visceral fat reduction and metabolic health.

Clinical Best Practices

  • Incorporate CVAI and LAP in routine assessments for T2DM risk.
  • Recognize the impact of sex on adiposity and T2DM associations.

Related Resources & Content

Original Source(s)

Related Content