Optimizing the Ocular Surface Before and After Cataract Surgery
The role of perfluorohexyloctane in dry eye management
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By
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Justin Schweitzer
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April 8, 2026
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Clinical Scorecard: Optimizing the Ocular Surface Before and After Cataract Surgery
At a Glance
| Category | Detail |
|---|
| Condition | Dry Eye Disease (DED) |
| Key Mechanisms | Use of perfluorohexyloctane ophthalmic solution (PFHO) to stabilize ocular surface and improve dry eye symptoms. |
| Target Population | Patients undergoing cataract surgery with dry eye disease. |
| Care Setting | Ophthalmology clinics and surgical centers. |
Key Highlights
- PFHO treatment did not negatively affect refractive outcomes.
- Significant improvement in ocular surface health and dry eye symptoms.
- Postoperative best-corrected visual acuity (BCVA) improved with continued PFHO therapy.
- High percentage of patients achieved optimal IOL calculation accuracy post-treatment.
- PFHO therapy resulted in normalization of OSDI scores by study end.
Guideline-Based Recommendations
Diagnosis
- Assess dry eye symptoms and ocular surface health preoperatively.
Management
- Utilize PFHO for managing dry eye before and after cataract surgery.
Monitoring & Follow-up
- Monitor ocular surface health and visual outcomes post-surgery.
Risks
- Consider potential impacts of untreated dry eye on surgical outcomes.
Patient & Prescribing Data
Patients with severe dry eye symptoms undergoing cataract surgery.
PFHO can be administered four times daily for 30 days pre- and postoperatively without compromising surgical measurements.
Clinical Best Practices
- Optimize ocular surface health before cataract surgery.
- Continue dry eye treatment postoperatively to enhance visual outcomes.
- Evaluate and document changes in ocular surface metrics and patient-reported outcomes.
References
