Frozen melanoma tissues yield extracellular vesicles with preserved diagnostic and immunogenic properties - Scorecard - MDSpire

Frozen melanoma tissues yield extracellular vesicles with preserved diagnostic and immunogenic properties

  • By

  • Daniele D´Arrigo

  • Kyong-Su Park

  • Cecilia Lässer

  • Georgios Panagiotis Sigalas

  • Emma Symonds

  • Ornella Urzí

  • Camilla Locatelli

  • Roger Olofsson Bagge

  • Jan Lötvall

  • Rossella Crescitelli

  • May 21, 2026

  • 0 min

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Clinical Scorecard: Cryopreserved melanoma samples produce extracellular vesicles that retain diagnostic and immunogenic characteristics

At a Glance

CategoryDetail
Condition
Key MechanismsExtracellular vesicles (EVs) mediate intercellular signaling and reflect the molecular state of their cells of origin.
Target Population
Care Setting

Key Highlights

    Guideline-Based Recommendations

    Diagnosis

      Management

        Monitoring & Follow-up

          Risks

            Patient & Prescribing Data

            Nine patients with stage III or IV melanoma.

            EVs isolated from both fresh and frozen tissues were compared for diagnostic and immunotherapeutic potential.

            Clinical Best Practices

              Related Resources & Content

              Original Source(s)

              Frozen melanoma tissues yield extracellular vesicles with preserved diagnostic and immunogenic properties

              • by Daniele D´Arrigo, Kyong-Su Park, Cecilia Lässer, Georgios Panagiotis Sigalas, Emma Symonds, Ornella Urzí, Camilla Locatelli, Roger Olofsson Bagge, Jan Lötvall, Rossella Crescitelli

              • May 21, 2026

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              Errors in the Table 2

              • May 1, 2026