Examining the Antibiotic Resistance Patterns of ESKAPE Pathogens from Human Sources in Africa: A Systematic Review and Meta-Analysis - Scorecard - MDSpire
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Examining the Antibiotic Resistance Patterns of ESKAPE Pathogens from Human Sources in Africa: A Systematic Review and Meta-Analysis

  • By

  • Ntelekwane George Khasapane

  • Sebolelo Jane Nkhebenyane

  • Kgaugelo Edward Lekota

  • Oriel Thekisoe

  • Tsepo Ramatla

  • December 22, 2025

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Clinical Scorecard: Examining the Antibiotic Resistance Patterns of ESKAPE Pathogens from Human Sources in Africa: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionAntibiotic Resistance (ABR) in ESKAPE Pathogens
Key Mechanisms
Target Population
Care Setting

Key Highlights

  • Significant increases in antibiotic resistance among ESKAPE pathogens in Africa observed over the past decade. [Add references]
  • High multidrug resistance rates reported, particularly in A. baumannii (84%) and K. pneumoniae (80%). [Add references]
  • Resistance to major antibiotic classes including carbapenems and glycopeptides is prevalent.

Guideline-Based Recommendations

Diagnosis

    Management

    • Implement stewardship programs to reduce misuse and overuse of antibiotics.
    • Consider additional strategies such as targeted therapy based on local resistance patterns.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Awareness of local resistance patterns is crucial for effective treatment choices. [Provide access methods]

        Clinical Best Practices

        • Adhere to infection control measures to prevent the spread of resistant pathogens, such as hand hygiene and isolation protocols.
        • Educate healthcare providers on the implications of antibiotic resistance.

        Related Resources & Content

        Original Source(s)

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