Building evidence on digital psychotherapies for adults living with depression: a systematic scoping review of populations, interventions and design features of ongoing and planned randomised controlled trials - Scorecard - MDSpire
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Building evidence on digital psychotherapies for adults living with depression: a systematic scoping review of populations, interventions and design features of ongoing and planned randomised controlled trials
Clinical Scorecard: Assessing the Landscape of Digital Psychotherapy Trials for Adult Depression: A Systematic Scoping Review of Current and Future Interventions, Populations, and Methodological Features
At a Glance
Category
Detail
Condition
Adult Depression
Key Mechanisms
Digital psychotherapies, including cognitive-behavioral therapy, delivered via digital devices.
Target Population
Adults with depressive disorders, bipolar depression, or depressive symptoms.
Care Setting
Research landscape of registered clinical trials.
Key Highlights
681 RCTs analyzed, with 51.8% completed and 34.1% published results.
Cognitive-behavioral therapy was the most frequent intervention (64.6%).
61.5% of trials relied on self-reported symptoms for inclusion.
Suicidal ideation was an exclusion criterion in 61.8% of trials.
Majority of trials concentrated in high-income countries.
Guideline-Based Recommendations
Diagnosis
Inclusion should involve clinician-based diagnosis rather than solely self-reported symptoms.
Management
Diversify types of evaluated psychotherapies beyond cognitive-behavioral therapy.
Monitoring & Follow-up
Timely dissemination of results and adherence to reporting practices.
Risks
Moderate to high risk of bias in many RCTs due to methodological limitations.
Patient & Prescribing Data
Adults with depressive disorders.
Digital psychotherapies may offer scalable treatment options but require robust evidence.
Clinical Best Practices
Utilize active controls in trials to strengthen evidence.
Focus on underserved populations with limited access to psychotherapy.
Ensure transparency in trial registration and reporting.
