Chlorine inhalation-induced ARDS treated with noninvasive ventilation and awake prone positioning: a case report - Scorecard - MDSpire
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Management of Chlorine-Induced Acute Respiratory Distress Syndrome with Noninvasive Ventilation and Prone Positioning: A Case Study

  • By

  • Yu E. Xue

  • Jianyue Zhang

  • Zanfeng Cao

  • Zuopeng Zhang

  • September 9, 2026

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Clinical Scorecard: Management of Chlorine-Induced Acute Respiratory Distress Syndrome with Noninvasive Ventilation and Prone Positioning: A Case Study

At a Glance

CategoryDetail
ConditionChlorine-Induced Acute Respiratory Distress Syndrome
Key MechanismsChlorine gas exposure leads to oxidative injury and inflammation in the respiratory system.
Target PopulationIndividuals exposed to high concentrations of chlorine gas, particularly in swimming pool environments.
Care SettingEmergency Intensive Care Unit (EICU)

Key Highlights

  • Chlorine exposure can lead to acute respiratory distress syndrome (ARDS).
  • Noninvasive mechanical ventilation and awake prone positioning were effective in treatment.
  • Complete recovery was achieved with comprehensive supportive care.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis of ARDS based on Berlin definition criteria.

Management

  • Utilization of noninvasive mechanical ventilation and prone positioning.
  • Administration of glucocorticoids and supportive care.

Monitoring & Follow-up

  • Close monitoring of oxygenation indices and vital signs.

Risks

  • High-concentration chlorine exposure poses significant health risks, including mortality.

Patient & Prescribing Data

A 76-year-old man with a history of coronary artery disease, hypertension, and type 2 diabetes.

Treatment included noninvasive ventilation, glucocorticoids, and strict fluid management.

Clinical Best Practices

  • Early recognition of chlorine exposure and ARDS symptoms.
  • Implementation of noninvasive ventilation strategies to avoid intubation.
  • Awake prone positioning to improve oxygenation.

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