Management of Chlorine-Induced Acute Respiratory Distress Syndrome with Noninvasive Ventilation and Prone Positioning: A Case Study
By
Yu E. Xue
Jianyue Zhang
Zanfeng Cao
Zuopeng Zhang
September 9, 2026
Clinical Scorecard: Management of Chlorine-Induced Acute Respiratory Distress Syndrome with Noninvasive Ventilation and Prone Positioning: A Case Study
At a Glance
Category Detail
Condition Chlorine-Induced Acute Respiratory Distress Syndrome
Key Mechanisms Chlorine gas exposure leads to oxidative injury and inflammation in the respiratory system.
Target Population Individuals exposed to high concentrations of chlorine gas, particularly in swimming pool environments.
Care Setting Emergency Intensive Care Unit (EICU)
Key Highlights
Chlorine exposure can lead to acute respiratory distress syndrome (ARDS). Noninvasive mechanical ventilation and awake prone positioning were effective in treatment. Complete recovery was achieved with comprehensive supportive care.
Guideline-Based Recommendations
Diagnosis
Diagnosis of ARDS based on Berlin definition criteria.
Management
Utilization of noninvasive mechanical ventilation and prone positioning. Administration of glucocorticoids and supportive care.
Monitoring & Follow-up
Close monitoring of oxygenation indices and vital signs.
Risks
High-concentration chlorine exposure poses significant health risks, including mortality.
Patient & Prescribing Data
A 76-year-old man with a history of coronary artery disease, hypertension, and type 2 diabetes.
Treatment included noninvasive ventilation, glucocorticoids, and strict fluid management.
Clinical Best Practices
Early recognition of chlorine exposure and ARDS symptoms. Implementation of noninvasive ventilation strategies to avoid intubation. Awake prone positioning to improve oxygenation.
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