Latent transition analysis of home-based fluid management during the vulnerable phase in patients with chronic heart failure: impact on symptom burden - Scorecard - MDSpire

Latent transition analysis of home-based fluid management during the vulnerable phase in patients with chronic heart failure: impact on symptom burden

  • By

  • Jing Zhang

  • Yuanyuan Cai

  • Xiang Li

  • Qingyun Song

  • Xuejiao Sun

  • Jinmei Yang

  • Haiyan Yu

  • June 4, 2026

  • 0 min

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Clinical Scorecard: Analysis of Latent Transitions in Home Fluid Management During Critical Periods in Chronic Heart Failure Patients: Effects on Symptom Burden

At a Glance

CategoryDetail
ConditionChronic Heart Failure (CHF)
Key MechanismsHome fluid management and symptom burden correlation
Target PopulationPatients with chronic heart failure, particularly post-discharge from acute decompensated heart failure
Care SettingCardiology department, post-hospital discharge

Key Highlights

  • Three latent profiles of home fluid management identified: high, medium, and low-level groups.
  • Significant transition rates among fluid management levels impacting symptom burden.
  • Persistent low and medium-level groups had higher risks of symptom burden compared to the high-level group.

Guideline-Based Recommendations

Diagnosis

  • Follow the Chinese Guidelines for the Diagnosis and Treatment of Heart Failure 2018.

Management

  • Implement effective home volume management strategies including salt intake limitation and fluid intake control.

Monitoring & Follow-up

  • Daily monitoring of body weight to manage fluid balance.

Risks

  • Increased risk of cardiovascular death and rehospitalization during the vulnerable phase post-discharge.

Patient & Prescribing Data

268 patients with chronic heart failure, aged 35 and older.

Volume management is critical to reduce symptom burden and readmission rates.

Clinical Best Practices

  • Tailor interventions based on individual patient characteristics and fluid management levels.
  • Focus on maintaining fluid balance to alleviate symptoms like dyspnea and edema.

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