The impact of health care on outcomes of suspected testicular torsion: results from the GRAND study - Scorecard - MDSpire

The impact of health care on outcomes of suspected testicular torsion: results from the GRAND study

  • By

  • Nikolaos Pyrgidis

  • Maria Apfelbeck

  • Regina Stredele

  • Severin Rodler

  • Marc Kidess

  • Yannic Volz

  • Philipp Weinhold

  • Christian G. Stief

  • Julian Marcon

  • Gerald B. Schulz

  • Michael Chaloupka

  • May 9, 2024

  • 0 min

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Clinical Scorecard: Evaluating the Role of Healthcare in Outcomes for Suspected Testicular Torsion: Findings from the GRAND Study

At a Glance

CategoryDetail
ConditionSuspected testicular torsion
Key MechanismsAcute twisting of the spermatic cord causing ischemia; requires immediate surgical exploration for testicular salvage
Target PopulationMales, predominantly younger than 25 years
Care SettingHospital inpatient surgical departments, primarily urology but also pediatric and general surgery

Key Highlights

  • Testicular torsion is a urological emergency with a testicular salvage rate of ~90% if detorsion occurs within 6 hours of symptom onset.
  • Among patients undergoing surgical exploration, 38% had detorsion with testicle preservation, 14% required orchiectomy, and 48% had no torsion identified.
  • Doppler ultrasound has high sensitivity (100%) and negative predictive value (100%) but surgical exploration remains the definitive exclusion method.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis is primarily clinical based on acute severe testicular pain and signs.
  • Doppler ultrasound can aid diagnosis with high sensitivity and specificity but cannot definitively exclude torsion without surgery.
  • Surgical exploration is mandatory to confirm or exclude testicular torsion.

Management

  • Immediate surgical exploration and detorsion with orchidopexy if torsion is confirmed.
  • Orchiectomy is required if testicular necrosis is present.
  • Patients without torsion may have alternative diagnoses such as torsion of appendix testis or epididymitis.

Monitoring & Follow-up

  • Monitor perioperative outcomes including length of hospital stay, transfusion requirements, and surgical wound infections.
  • Adjust management based on patient comorbidities such as diabetes, obesity, and cryptorchidism.

Risks

  • Delayed detorsion beyond 6 hours significantly reduces testicular salvage rates.
  • Higher rates of orchiectomy are associated with comorbidities including diabetes, chronic kidney disease, hypertension, obesity, and cryptorchidism.
  • Non-urological departments may have different perioperative outcomes compared to urology.

Patient & Prescribing Data

81,899 males undergoing surgical exploration for suspected testicular torsion in Germany (2005–2021), median age 16 years

38% underwent detorsion with testicle preservation; 14% required orchiectomy; 48% had no torsion. Comorbidities influenced risk of orchiectomy.

Clinical Best Practices

  • Prioritize rapid surgical exploration within 6 hours of symptom onset to maximize testicular salvage.
  • Use Doppler ultrasound as an adjunct but do not delay surgery if clinical suspicion is high.
  • Consider patient comorbidities in perioperative risk assessment and management planning.
  • Prefer treatment in urology departments due to greater surgical expertise with male genitalia.
  • Recognize alternative diagnoses in patients without torsion to guide appropriate care.

References

Original Source(s)

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