First HIV-Positive-to-HIV-Positive Lung Transplant Reported - Scorecard - MDSpire

First HIV-Positive-to-HIV-Positive Lung Transplant Reported

The procedure was performed under a HOPE Act research protocol at an NYU Langone Health center the institution said is among the limited number of US transplant centers equipped and approved to perform HOPE lung transplants.

  • By

  • Kathryn Wighton

  • June 19, 2026

  • 3 min

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Clinical Scorecard: First HIV-Positive-to-HIV-Positive Lung Transplant Reported

At a Glance

CategoryDetail
ConditionHuman Immunodeficiency Virus (HIV)
Key MechanismsLung transplantation in HIV-positive patients
Target PopulationIndividuals living with HIV requiring lung transplants
Care SettingTransplant centers equipped for HOPE lung transplants

Key Highlights

  • First reported lung transplant from HIV-positive to HIV-positive recipient
  • Recipient had HIV for nearly 26 years and suffered from sarcoidosis and pneumonia
  • Transplant performed at NYU Langone Transplant Institute
  • Procedure included simultaneous liver transplant
  • Significant advancement for organ transplantation equity in the HIV-positive community

Guideline-Based Recommendations

Diagnosis

  • Evaluate HIV-positive patients for transplant eligibility based on overall health and organ function

Management

  • Consider dual-organ transplantation for patients with complex health issues

Monitoring & Follow-up

  • Post-transplant monitoring for organ function and HIV management

Risks

  • Potential complications from transplantation in HIV-positive patients

Patient & Prescribing Data

Approximately 1.2 million people living with HIV in the United States

Advances in antiretroviral therapy allow for long, healthy lives and reduced transmission risk

Clinical Best Practices

  • Utilize research protocols for organ transplantation in HIV-positive patients
  • Ensure comprehensive evaluation of potential transplant recipients

Related Resources & Content

Original Source(s)

First HIV-Positive-to-HIV-Positive Lung Transplant Reported

  • by Kathryn Wighton

  • June 19, 2026

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