Perioperative anesthetic management in pediatric heart transplantation: a single-center descriptive study involving 27 patients - Scorecard - MDSpire

Perioperative anesthetic management in pediatric heart transplantation: a single-center descriptive study involving 27 patients

  • By

  • Ya-fei Cheng

  • Cong-li Meng

  • Yi-ru Wang

  • Lin Chen

  • Ya-qun Ma

  • Wen-zhi Guo

  • Hang Guo

  • June 18, 2026

  • 0 min

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Clinical Scorecard: Anesthetic Approaches During the Perioperative Period in Pediatric Heart Transplantation: A Descriptive Analysis of 27 Cases at a Single Institution

At a Glance

CategoryDetail
ConditionPediatric heart transplantation
Key MechanismsPerioperative anesthesia management strategies including low-dose staged induction and invasive monitoring.
Target PopulationPediatric patients under 18 years undergoing orthotopic heart transplantation.
Care SettingSingle-center, retrospective observational study.

Key Highlights

  • 27 pediatric patients included, aged 6 months to 16 years.
  • Dilated cardiomyopathy was the most common diagnosis (74.1%).
  • Preoperative ECMO support used in 55.6% of patients.
  • 85.2% survival rate at follow-up with major complications observed.

Guideline-Based Recommendations

Diagnosis

  • Patients diagnosed with end-stage heart disease requiring transplantation.

Management

  • Utilization of low-dose staged induction and invasive monitoring during anesthesia.

Monitoring & Follow-up

  • Close monitoring for complications such as hypoxic-ischemic encephalopathy and AKI.

Risks

  • Potential for major complications including hypoxic-ischemic encephalopathy, AKI requiring CRRT, and peripheral nerve injury.

Patient & Prescribing Data

Pediatric heart transplant recipients with severe conditions.

Multidisciplinary collaboration is essential for managing complex cases.

Clinical Best Practices

  • Implement low-dose staged induction for anesthesia.
  • Ensure invasive monitoring during the perioperative period.
  • Collaborate across disciplines for optimal patient management.

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