Effects of Drug-Coated Balloons on Stenosis of the Left Anterior Descending Artery Near Myocardial Bridges
By
Yuqing Jia
Yangfeng Xie
Ying Li
Huaipeng Zhang
Yanfen Li
Weiming Li
Chuang Li
Yixing Yang
Wenhao Jia
Wenbo Han
August 24, 2026
Clinical Scorecard: Effects of Drug-Coated Balloons on Stenosis of the Left Anterior Descending Artery Near Myocardial Bridges
At a Glance
Category Detail
Condition LAD artery stenosis proximal to myocardial bridge Key Mechanisms Drug-coated balloons (DCBs) reduce intimal inflammation and thrombosis risk without permanent metal implantation. Target Population Patients with LAD artery stenosis proximal to a myocardial bridge treated between January 2020 and July 2021. Care Setting Cardiology interventional procedures
Key Highlights
No statistically significant difference in MACE-free survival between DCB and DES groups. 73.96% MACE-free survival for DCB group vs. 82.49% for DES group. Cox regression showed no significant difference in MACEs (HR = 1.58, P = 0.383). Sample size was limited, and results are preliminary. Larger prospective studies are needed to validate findings. Guideline-Based Recommendations
Diagnosis
Diagnosis of myocardial bridge requires compression of a segment by surrounding muscle contraction during systole. Management
Stent implantation is the principal treatment for stenosis proximal to a myocardial bridge. Monitoring & Follow-up
Monitor for major adverse cardiac events (MACEs) post-intervention. Risks
In-stent restenosis remains a complication in treating stenosis proximal to myocardial bridges. Patient & Prescribing Data
Patients aged ≤85 years with significant stenosis (>70%) in LAD artery proximal to MB.
Patients in the DCB group received Paclitaxel-Coated Balloons and transitioned to single antiplatelet therapy after 3 months.
Clinical Best Practices
Utilize quantitative coronary angiography (QCA) to determine percentage stenoses. Perform routine pre-dilatation with a standard balloon before DCB treatment. Ensure TIMI blood flow grade III and residual stenosis ≤30% before DCB application. Related Resources & Content
