Advancements in Repetitive Transcranial Magnetic Stimulation: An Overview of Clinical Evidence and Patient Feedback on ExoTMS
By
David Pánek
Václav Gerla
Michelle Dees
Yael Halaas
JD McCoy
Louis Cady
Rakesh Nanda
Rudolph Eberwein
Henry Johnston
Nick Tvrdik
Georgine Nanos
Charmi Patel
Melinda Silva
July 20, 2026
Clinical Scorecard: Advancements in Repetitive Transcranial Magnetic Stimulation: An Overview of Clinical Evidence and Patient Feedback on ExoTMS
At a Glance
Category Detail
Condition Transcranial Magnetic Stimulation (TMS) Key Mechanisms Non-invasive neuromodulation technique leveraging electromagnetic induction to induce electrical currents in neural tissue. Target Population Patients with psychiatric and neurological disorders. Care Setting Clinical settings utilizing neuromodulation therapies.
Key Highlights
ExoTMS shows high patient satisfaction and comfort during treatment. 93.3% of participants reported the therapy as comfortable with minimal pain. Improvements in well-being, mood, perceived stress, and mental energy were noted. No serious adverse events were reported during the studies. ExoTMS may offer advantages over conventional TMS in treatment efficiency. Guideline-Based Recommendations
Diagnosis
TMS is indicated for treatment-resistant major depressive disorder and other psychiatric and neurological disorders. Management
Treatment protocols typically consist of 20-30 sessions for optimal outcomes. Monitoring & Follow-up
Follow-up assessments should be conducted at 1 month and, if applicable, at 3 months post-treatment. Risks
Mild to moderate scalp discomfort may occur depending on stimulation parameters. Patient & Prescribing Data
182 active-treated participants in included studies.
High tolerability and comfort reported, with significant improvements in various mental health domains.
Clinical Best Practices
Ensure precise coil positioning to enhance treatment efficacy. Utilize integrated navigation systems to reduce setup time and variability. Related Resources & Content
