Efficacy and safety of robotic-assisted laparoscopic “one-step” radical nephroureterectomy and bladder cuff excision - Scorecard - MDSpire

Efficacy and safety of robotic-assisted laparoscopic “one-step” radical nephroureterectomy and bladder cuff excision

  • By

  • Liao Chunyu

  • Zhao Tonglei

  • Peng Xinyang

  • Chen Kangkang

  • Mao Weipu

  • Zhang Dakun

  • Chen Ming

  • Wu Jianping

  • May 7, 2025

  • 0 min

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Clinical Scorecard: Effectiveness and safety of robotic-assisted laparoscopic radical nephroureterectomy with bladder cuff resection in a single procedure

At a Glance

CategoryDetail
ConditionUpper tract urothelial carcinoma (UTUC)
Key MechanismsRobotic-assisted laparoscopic radical nephroureterectomy (RNU) with bladder cuff excision (BCE) performed in a single-step procedure without repositioning or robot redocking
Target PopulationPatients diagnosed with high-risk UTUC confirmed by imaging and pathology
Care SettingSurgical treatment in a tertiary hospital urology department with robotic surgery capabilities

Key Highlights

  • UTUC is a rare and invasive uroepithelial carcinoma often diagnosed at advanced stages with poor prognosis.
  • Robotic-assisted laparoscopic one-step RNU with BCE reduces trauma and accelerates recovery compared to open surgery.
  • The single-step robotic procedure avoids intraoperative repositioning and robot redocking, improving surgical efficiency.

Guideline-Based Recommendations

Diagnosis

  • Preoperative imaging with MRI or enhanced CT to confirm UTUC and exclude distant metastases.
  • Postoperative pathological confirmation of UTUC.

Management

  • Radical nephroureterectomy with bladder cuff excision is the standard surgical treatment for high-risk UTUC.
  • Robotic-assisted laparoscopic one-step RNU with BCE is a safe and effective minimally invasive alternative to open surgery.

Monitoring & Follow-up

  • Follow-up for at least 12 months postoperatively to monitor for tumor recurrence and complications.

Risks

  • Incomplete tumor resection can lead to postoperative tumor recurrence.
  • Potential risks related to surgical trauma and positioning must be managed carefully.

Patient & Prescribing Data

69 patients with UTUC undergoing robotic-assisted laparoscopic one-step RNU from 2019 to 2023

The procedure was performed by experienced surgeons with careful trocar placement and patient positioning, demonstrating feasibility and safety.

Clinical Best Practices

  • Position patient in 45° semirecumbent on healthy side with appropriate limb positioning to avoid vascular nerve compression.
  • Use specific trocar placement to optimize robotic instrument access without repositioning.
  • Ligate ureter early to prevent urine spillage and tumor cell migration.
  • Preposition barbed sutures before bladder mucosa incision to facilitate bladder cuff excision and closure.
  • Ensure complete resection of kidney, ureter, and bladder cuff to minimize recurrence risk.

References

Original Source(s)

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