Removal of Implantable Collamer Lenses Due to Elevated Intraocular Pressure in a Patient with Severe Hyperopia: A Case Study - Scorecard - MDSpire
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Removal of Implantable Collamer Lenses Due to Elevated Intraocular Pressure in a Patient with Severe Hyperopia: A Case Study

  • By

  • Liuqing Cui

  • Karl Mercieca

  • Leonie Bourauel

  • March 24, 2026

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Clinical Scorecard: Removal of Implantable Collamer Lenses Due to Elevated Intraocular Pressure in a Patient with Severe Hyperopia: A Case Study

At a Glance

CategoryDetail
ConditionElevated intraocular pressure (IOP) and angle closure following Implantable Collamer Lens (ICL) implantation in severe hyperopia
Key MechanismsICLs without central aperture causing angle closure, peripheral anterior synechiae, iris adhesions leading to IOP elevation and risk of secondary glaucoma
Target PopulationPatients with high hyperopia and astigmatism who have undergone ICL implantation
Care SettingOphthalmology clinics with surgical and medical glaucoma management capabilities

Key Highlights

  • ICL implantation without central port can lead to long-term complications including elevated IOP and secondary angle closure glaucoma.
  • Medical therapy with multiple IOP-lowering agents may be insufficient to control IOP in some patients after ICL implantation.
  • Combined explantation of ICL and cataract surgery with posterior chamber IOL implantation can effectively reduce IOP and inflammation.

Guideline-Based Recommendations

Diagnosis

  • Perform slit-lamp examination to assess ICL position and iris adhesions.
  • Use gonioscopy to evaluate chamber angle status and presence of peripheral anterior synechiae.
  • Conduct visual field testing and OCT to assess for glaucomatous damage.

Management

  • Initiate IOP-lowering medications including prostaglandin analogs, carbonic anhydrase inhibitors, and alpha-agonists.
  • Consider combined surgical explantation of ICL and phacoemulsification with posterior chamber IOL implantation in cases of inadequate IOP control or angle closure.
  • Administer perioperative anti-inflammatory treatment including topical steroids and subconjunctival dexamethasone.

Monitoring & Follow-up

  • Regular follow-up every 3-4 months to monitor IOP and anterior chamber inflammation.
  • Assess visual acuity and anterior chamber reaction postoperatively.
  • Monitor for postoperative complications such as fibrin deposition and iris defects.

Risks

  • Risk of iris trauma and prolapse during ICL explantation due to adhesions.
  • Potential postoperative inflammation requiring intensive steroid therapy.
  • Loss of accommodation following cataract surgery with posterior chamber IOL implantation.

Patient & Prescribing Data

38-year-old woman with high hyperopia and family history of glaucoma post-ICL implantation

Multiple IOP-lowering agents (bimatoprost, dorzolamide, clonidine) were insufficient; surgical explantation combined with cataract surgery improved IOP control and visual acuity.

Clinical Best Practices

  • Careful preoperative assessment of angle status and iris adhesions before ICL explantation.
  • Use of iris retractors and intravenous mannitol to minimize intraoperative iris trauma.
  • Aggressive postoperative anti-inflammatory therapy including topical steroids and subconjunctival injections to control inflammation.
  • Patient counseling regarding risks of surgery, loss of accommodation, and potential postoperative visual symptoms such as glare.

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