Guidelines from Experts on the Strategic Use of Isotretinoin for Optimal Acne Management: Recommendations from the ERAISE ACNE Consensus - Scorecard - MDSpire

Guidelines from Experts on the Strategic Use of Isotretinoin for Optimal Acne Management: Recommendations from the ERAISE ACNE Consensus

  • By

  • Sanjiv Kandhari

  • Jayakar Thomas

  • Niti Khunger

  • Maya Vedamurthy

  • Kiran Godse

  • Abir Saraswat

  • Nina Madnani

  • Vijay Somani

  • Sushil Tahiliani

  • Bela Shah

  • C. R. Srinivas

  • Asit Mittal

  • Mukesh Girdhar

  • Maleeka Sachdeva

  • Sachin Varma

  • Manjunath Shenoy

  • Shyamanta Barua

  • Abhishek De

  • Akshay Jain

  • Aseem Sharma

  • March 31, 2026

  • 0 min

Share

Clinical Scorecard: Guidelines from Experts on the Strategic Use of Isotretinoin for Optimal Acne Management: Recommendations from the ERAISE ACNE Consensus

At a Glance

CategoryDetail
ConditionAcne vulgaris
Key MechanismsFollicular hyperkeratinization, increased sebum production, C. acnes proliferation, inflammation.
Target PopulationAdults and adolescents with severe conglobate, nodulocystic, and severe papulopustular acne.
Care SettingDermatology clinics in regions with similar patient settings to India.

Key Highlights

  • Isotretinoin is the gold standard for severe acne management.
  • Early initiation after failure of first-line therapy is recommended.
  • Risk-adapted laboratory monitoring is emphasized.
  • Conventional dosing of 0.5–1 mg/kg/day is preferred for severe cases.
  • Procedures like comedone extraction and chemical peels can be used during therapy.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis based on severity and risk factors.

Management

  • Isotretinoin recommended for severe, scarring, or treatment-refractory acne.

Monitoring & Follow-up

  • Risk-adapted laboratory monitoring rather than universal protocols.

Risks

  • Concerns include teratogenicity, mucocutaneous side effects, dyslipidemia, and hepatotoxicity.

Patient & Prescribing Data

Patients with severe acne and select moderate cases.

Isotretinoin can improve quality of life and reduce scarring.

Clinical Best Practices

  • Educate patients on adherence and avoidance of lesion manipulation.
  • Incorporate adjuvant care such as gentle cleansers and non-comedogenic moisturizers.

Related Resources & Content

Original Source(s)

Guidelines from Experts on the Strategic Use of Isotretinoin for Optimal Acne Management: Recommendations from the ERAISE ACNE Consensus

  • by Sanjiv Kandhari, Jayakar Thomas, Niti Khunger, Maya Vedamurthy, Kiran Godse, Abir Saraswat, Nina Madnani, Vijay Somani, Sushil Tahiliani, Bela Shah, C. R. Srinivas, Asit Mittal, Mukesh Girdhar, Maleeka Sachdeva, Sachin Varma, Manjunath Shenoy, Shyamanta Barua, Abhishek De, Akshay Jain, Aseem Sharma

  • March 31, 2026

Related Content

Hospital Prices Posted. Few Patients Look.

Federal rules require hospitals to post prices so patients can shop. Instead, insurers and providers use the data to negotiate what they get paid.

Efficacy Assessment of Intradermal Stromal Vascular Fraction Injection Compared to Saline Injection for Treating Atrophic Acne Scars: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Study

Fabricated Citations Are Reaching Medical Journals

A large audit of biomedical publications suggests fabricated references are increasingly appearing in peer-reviewed papers — often in ways that are difficult for reviewers and readers to detect.