Re: Estimation of opioid misuse prevalence in New York State counties, 2007-2018. A Bayesian spatio-temporal abundance model approach - Scorecard - MDSpire
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Re: Estimation of opioid misuse prevalence in New York State counties, 2007-2018. A Bayesian spatio-temporal abundance model approach
Clinical Scorecard: Assessment of Opioid Misuse Rates Across New York State Counties from 2007 to 2018 Using a Bayesian Spatio-Temporal Model
At a Glance
Category
Detail
Condition
Opioid Misuse (OM)
Key Mechanisms
Modeling opioid misuse prevalence using surveillance data and Bayesian spatio-temporal methods
Target Population
Residents of New York State counties, including subpopulations affected by opioid misuse
Care Setting
Public health surveillance and epidemiologic monitoring
Key Highlights
Incorrect definition and coding of opioid overdose emergency department visits can bias model inputs.
National Survey on Drug Use and Health (NSDUH) data may underestimate opioid misuse due to underrepresentation and self-report bias.
Collaboration between public health agencies and academic partners is essential for accurate modeling and data interpretation.
Guideline-Based Recommendations
Diagnosis
Use ICD-10-CM T codes specific to opioid substances (T40.0, T40.1, T40.2, T40.3, T40.4, T40.6) for identifying opioid overdose events.
Exclude X and Y ICD-10 codes related to poisoning deaths and visits coded as 'adverse effect' or 'sequela' from overdose counts.
Management
Incorporate multiple data sources including administrative health data and surveys to improve opioid misuse prevalence estimates.
Engage in public health-academic partnerships to access granular data and improve model accuracy.
Monitoring & Follow-up
Provide convergence diagnostics and goodness-of-fit statistics when modeling opioid misuse prevalence.
Consider age range specifications in model inputs to ensure consistency with survey data.
Risks
Bias in prevalence estimates due to underrepresentation of homeless, incarcerated, and non-responding individuals in surveys.
Potential inaccuracies from using aggregated data without person-level linkage across systems.
Patient & Prescribing Data
New York State residents with potential opioid misuse, including underrepresented groups such as homeless and incarcerated individuals
Current prevalence estimates may underestimate true opioid misuse burden; improved data linkage and modeling approaches are needed to inform resource allocation and interventions.
Clinical Best Practices
Use validated ICD-10-CM codes specific to opioid overdose for surveillance and research.
Collaborate with public health agencies to obtain detailed administrative data for modeling.
Interpret modeled opioid misuse prevalence with caution, acknowledging limitations of survey data and model inputs.
Invest in public health-academic partnerships to enhance data quality and modeling methodologies.
In a target-trial emulation of more than 600,000 veterans, GLP-1 RA initiators saw fewer new substance use disorders—and patients with existing SUDs had fewer overdoses, hospitalizations, and deaths.