Comparison of early clinical and optical quality-related outcomes after SMILE using VisuMax 800 versus VisuMax 500 for myopia and low-to-moderate astigmatism in a Chinese population: a single-center retrospective study - Scorecard - MDSpire

Comparison of early clinical and optical quality-related outcomes after SMILE using VisuMax 800 versus VisuMax 500 for myopia and low-to-moderate astigmatism in a Chinese population: a single-center retrospective study

  • By

  • Xuanyu Yang

  • Jiabin Leng

  • Yuchen Mei

  • Fei Peng

  • Yifan Xie

  • Linlin Liu

  • Linhua Wan

  • Liping Liu

  • Wentian Zhou

  • Hui Zhang

  • April 30, 2026

Share

Clinical Scorecard: Evaluation of Initial Clinical Outcomes and Optical Quality Metrics Following SMILE with VisuMax 800 Compared to VisuMax 500 for Myopia and Low-to-Moderate Astigmatism in a Chinese Cohort: A Retrospective Single-Center Analysis

At a Glance

CategoryDetail
ConditionMyopia and Low-to-Moderate Astigmatism
Key MechanismsSmall incision lenticule extraction (SMILE) using femtosecond laser technology
Target PopulationChinese patients undergoing SMILE
Care SettingSingle-center, retrospective study

Key Highlights

  • No significant differences in visual acuity or safety between VisuMax 500 and 800 groups
  • SMILE Pro (VisuMax 800) showed shorter lenticule creation time
  • Lower optical zone decentration and postoperative vertical coma in SMILE Pro group
  • Lower residual cylindrical error and improved astigmatism vector outcomes with SMILE Pro
  • Exploratory analysis indicated associations between decentration and optical outcomes

Guideline-Based Recommendations

Diagnosis

  • Assess myopia and low-to-moderate astigmatism for suitability for SMILE

Management

  • Consider SMILE Pro (VisuMax 800) for improved centration and optical outcomes

Monitoring & Follow-up

  • Monitor visual acuity, refractive outcomes, and optical quality metrics postoperatively

Risks

  • Potential for suction loss, cap-related complications, and higher-order aberrations

Patient & Prescribing Data

200 patients with myopia and low-to-moderate astigmatism

Both platforms demonstrated favorable safety and efficacy; however, SMILE Pro showed advantages in specific optical metrics

Clinical Best Practices

  • Utilize the VisuMax 800 platform for enhanced centration accuracy
  • Perform thorough preoperative assessments to identify suitable candidates
  • Conduct postoperative follow-ups to evaluate visual and optical outcomes

Related Resources & Content

Original Source(s)

Comparison of early clinical and optical quality-related outcomes after SMILE using VisuMax 800 versus VisuMax 500 for myopia and low-to-moderate astigmatism in a Chinese population: a single-center retrospective study

  • by Xuanyu Yang, Jiabin Leng, Yuchen Mei, Fei Peng, Yifan Xie, Linlin Liu, Linhua Wan, Liping Liu, Wentian Zhou, Hui Zhang

  • April 30, 2026

Related Content

A Strategic Shift in Vision Healthcare

The clinical and financial imperative for surgical vision correction over conventional optical aids

The Power of Adjustability

Sitting Down With… Ron Kurtz, President and Chief Executive Officer, RxSight

No-Fee CE: Specialty Lens Matchmaking 101

This no-fee CE article reviews the multiple factors that a practitioner should consider when fitting specialty contact lenses in order to optimize visual outcomes, patient comfort, and ocular health.