Comparison of early clinical and optical quality-related outcomes after SMILE using VisuMax 800 versus VisuMax 500 for myopia and low-to-moderate astigmatism in a Chinese population: a single-center retrospective study - Scorecard - MDSpire
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Evaluation of Initial Clinical Outcomes and Optical Quality Metrics Following SMILE with VisuMax 800 Compared to VisuMax 500 for Myopia and Low-to-Moderate Astigmatism in a Chinese Cohort: A Retrospective Single-Center Analysis

  • By

  • Xuanyu Yang

  • Jiabin Leng

  • Yuchen Mei

  • Fei Peng

  • Yifan Xie

  • Linlin Liu

  • Linhua Wan

  • Liping Liu

  • Wentian Zhou

  • Hui Zhang

  • April 30, 2026

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Clinical Scorecard: Evaluation of Initial Clinical Outcomes and Optical Quality Metrics Following SMILE with VisuMax 800 Compared to VisuMax 500 for Myopia and Low-to-Moderate Astigmatism in a Chinese Cohort: A Retrospective Single-Center Analysis

At a Glance

CategoryDetail
ConditionMyopia and Low-to-Moderate Astigmatism
Key MechanismsSmall incision lenticule extraction (SMILE) using femtosecond laser technology
Target PopulationChinese patients undergoing SMILE
Care SettingSingle-center, retrospective study

Key Highlights

  • No significant differences in visual acuity or safety between VisuMax 500 and 800 groups
  • SMILE Pro (VisuMax 800) showed shorter lenticule creation time
  • Lower optical zone decentration and postoperative vertical coma in SMILE Pro group
  • Lower residual cylindrical error and improved astigmatism vector outcomes with SMILE Pro
  • Exploratory analysis indicated associations between decentration and optical outcomes

Guideline-Based Recommendations

Diagnosis

  • Assess myopia and low-to-moderate astigmatism for suitability for SMILE

Management

  • Consider SMILE Pro (VisuMax 800) for improved centration and optical outcomes

Monitoring & Follow-up

  • Monitor visual acuity, refractive outcomes, and optical quality metrics postoperatively

Risks

  • Potential for suction loss, cap-related complications, and higher-order aberrations

Patient & Prescribing Data

200 patients with myopia and low-to-moderate astigmatism

Both platforms demonstrated favorable safety and efficacy; however, SMILE Pro showed advantages in specific optical metrics

Clinical Best Practices

  • Utilize the VisuMax 800 platform for enhanced centration accuracy
  • Perform thorough preoperative assessments to identify suitable candidates
  • Conduct postoperative follow-ups to evaluate visual and optical outcomes

Related Resources & Content

Original Source(s)

Comparison of early clinical and optical quality-related outcomes after SMILE using VisuMax 800 versus VisuMax 500 for myopia and low-to-moderate astigmatism in a Chinese population: a single-center retrospective study

  • by Xuanyu Yang, Jiabin Leng, Yuchen Mei, Fei Peng, Yifan Xie, Linlin Liu, Linhua Wan, Liping Liu, Wentian Zhou, Hui Zhang

  • April 30, 2026

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