Penetrating keratoplasty combined with intrascleral fixation of a four-haptic intraocular lens in aphakic eyes with corneal pathology - Scorecard - MDSpire

Penetrating keratoplasty combined with intrascleral fixation of a four-haptic intraocular lens in aphakic eyes with corneal pathology

  • By

  • Chang Xu

  • Shuying Liao

  • Wei Wang

  • Zhuo Chen

  • Xiaochun Mao

  • Guigang Li

  • June 26, 2026

  • 0 min

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Clinical Scorecard: Combined Penetrating Keratoplasty and Intrascleral Fixation of a Four-Haptic Intraocular Lens in Aphakic Patients with Corneal Disorders

At a Glance

CategoryDetail
ConditionAphakia with corneal pathology
Key MechanismsCombined penetrating keratoplasty (PKP) and intrascleral fixation of a four-haptic intraocular lens (IOL)
Target PopulationAphakic patients with corneal disorders and insufficient capsular support
Care SettingOphthalmology department

Key Highlights

  • Mean BCVA improved from 3.00 logMAR preoperatively to 1.04 logMAR at 6 months.
  • Four of five grafts remained clear at 6 months.
  • All IOLs remained centered and stable postoperatively.
  • No major intraoperative complications occurred.
  • Mean ECD at 6 months was 2,445 cells/mm2.

Guideline-Based Recommendations

Diagnosis

  • Assessment of corneal pathology and capsular support in aphakic eyes.

Management

  • Consider combined PKP and intrascleral fixation of a four-haptic IOL for selected patients.

Monitoring & Follow-up

  • Regular follow-up for BCVA, IOP, graft clarity, ECD, and IOL position.

Risks

  • Potential for complications related to surgery and graft failure.

Patient & Prescribing Data

Five consecutive aphakic patients with corneal disorders.

Topical corticosteroids, antibiotic eye drops, and tacrolimus eye drops were used postoperatively.

Clinical Best Practices

  • Perform thorough preoperative assessment of corneal and ocular health.
  • Ensure proper IOL centration during surgery.
  • Implement a tapering regimen for postoperative medications.

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