Association between the C-reactive protein-triglyceride-glucose index and the presence and prognosis of coronary microvascular dysfunction in patients with chronic coronary syndrome - Scorecard - MDSpire
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Association between the C-reactive protein-triglyceride-glucose index and the presence and prognosis of coronary microvascular dysfunction in patients with chronic coronary syndrome
Clinical Scorecard: Link Between C-Reactive Protein-Triglyceride-Glucose Index and Coronary Microvascular Dysfunction Prognosis in Chronic Coronary Syndrome Patients
At a Glance
Category
Detail
Condition
Coronary Microvascular Dysfunction in Chronic Coronary Syndrome
Key Mechanisms
Insulin resistance and inflammation as contributors to CMD and cardiovascular risk.
Target Population
Patients with chronic coronary syndrome undergoing coronary angiography.
Care Setting
Single-center retrospective cohort study.
Key Highlights
CTI is independently associated with CMD and MACE in CCS patients.
Higher CTI predicts increased MACE risk, especially in CMD patients.
CTI demonstrates superior predictive accuracy for CMD-related MACE compared to TyG.
Guideline-Based Recommendations
Diagnosis
CMD defined by caIMR ≥ 25 U.
Management
Use CTI for early risk stratification and personalized management in CMD.
Monitoring & Follow-up
Follow-up for MACE risk assessment over a median of 35 months.
Risks
Increased risk of MACE associated with higher CTI levels.
Patient & Prescribing Data
Adults over 18 years with suspected or confirmed chronic coronary syndrome.
CTI integrates TyG and CRP for a comprehensive cardiovascular risk assessment.
Clinical Best Practices
Assess CMD using coronary angiography-derived index of microcirculatory resistance (caIMR).
Consider CTI as a biomarker for CMD and MACE risk in clinical practice.
