Assessing the efficacy of ultrasound-guided platelet-rich plasma on nerve regeneration and functional outcomes in forearm peripheral nerve injuries: a retrospective observational study - Scorecard - MDSpire

Assessing the efficacy of ultrasound-guided platelet-rich plasma on nerve regeneration and functional outcomes in forearm peripheral nerve injuries: a retrospective observational study

  • By

  • Qing Li

  • Cong Zou

  • Wenjie Liu

  • Lingling Zuo

  • Hui Long

  • Wei Gao

  • Bin Liu

  • July 6, 2026

  • 0 min

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Clinical Scorecard: Evaluating the Impact of Ultrasound-Guided Platelet-Rich Plasma Therapy on Nerve Regeneration and Functional Recovery in Forearm Peripheral Nerve Injuries: A Retrospective Observational Analysis

At a Glance

CategoryDetail
ConditionPeripheral Nerve Injuries (PNI)
Key MechanismsUltrasound-guided platelet-rich plasma (PRP) treatment enhances nerve regeneration and functional recovery.
Target PopulationPatients with unilateral forearm median or ulnar nerve injuries classified as grade II or III.
Care SettingRetrospective analysis in a clinical hospital setting.

Key Highlights

  • PRP group showed significantly larger nerve cross-sectional diameter and area compared to conventional group.
  • DASH scores were significantly lower in the PRP group at 2 months post-treatment.
  • PRP group exhibited higher sensory and motor conduction velocities.
  • Serum levels of BDNF, NGF, and NT-3 were significantly elevated in the PRP group.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis of PNI confirmed through clinical and electrophysiological evaluation.

Management

  • Consider ultrasound-guided PRP as an adjunctive therapy for enhancing nerve regeneration.

Monitoring & Follow-up

  • Assess nerve cross-sectional diameter, area, and DASH scores post-treatment.

Risks

  • Potential for incomplete recovery despite treatment.

Patient & Prescribing Data

183 patients with unilateral forearm median or ulnar nerve injuries.

PRP treatment may improve functional outcomes and nerve regeneration compared to conventional rehabilitation.

Clinical Best Practices

  • Utilize ultrasound guidance for precise PRP injection to enhance treatment efficacy.
  • Monitor both objective and subjective measures of recovery post-treatment.

Related Resources & Content

Original Source(s)

Assessing the efficacy of ultrasound-guided platelet-rich plasma on nerve regeneration and functional outcomes in forearm peripheral nerve injuries: a retrospective observational study

  • by Qing Li, Cong Zou, Wenjie Liu, Lingling Zuo, Hui Long, Wei Gao, Bin Liu

  • July 6, 2026

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