Successful treatment of refractory focal eosinophilic myositis with extra-ocular muscle involvement using tocilizumab: a case report - Summary - MDSpire

Successful treatment of refractory focal eosinophilic myositis with extra-ocular muscle involvement using tocilizumab: a case report

  • By

  • Haijun Liu

  • Qianhua Li

  • Xia Ouyang

  • Shuyu Chen

  • Henglun Liang

  • Yufeng Ye

  • Huiyuan Cao

  • Yong Xue

  • Lie Dai

  • May 25, 2026

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Objective:

To report a case of multifocal focal eosinophilic myositis (FEM) with extra-ocular muscle involvement.

Key Findings:
  • The patient exhibited isolated extra-ocular muscle involvement.
  • Tocilizumab treatment led to improvement in diplopia, ocular motility, and reduction in muscle swelling on MRI.
Interpretation:

Extra-ocular muscle involvement in FEM may indicate a more treatment-resistant phenotype.

Limitations:
  • This is a single case study, limiting generalizability.
  • Long-term efficacy and safety of tocilizumab in this context remain to be established.
Conclusion:

Tocilizumab may represent a therapeutic strategy for refractory cases of FEM with extra-ocular muscle involvement.

Original Source(s)

Successful treatment of refractory focal eosinophilic myositis with extra-ocular muscle involvement using tocilizumab: a case report

  • by Haijun Liu, Qianhua Li, Xia Ouyang, Shuyu Chen, Henglun Liang, Yufeng Ye, Huiyuan Cao, Yong Xue, Lie Dai

  • May 25, 2026

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