Impact of the COVID-19 pandemic on the pattern of acute appendicitis, a single-center study - Summary - MDSpire

Impact of the COVID-19 pandemic on the pattern of acute appendicitis, a single-center study

  • By

  • Khaled A. Obeidat

  • Rami A. Saadeh

  • Renad Y. Msameh

  • May 15, 2026

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Objective:

To assess variations in the frequency, clinical manifestations, and surgical techniques of appendectomies conducted during the COVID-19 lockdown in relation to a pre-pandemic timeframe, highlighting the significance of timely medical intervention.

Key Findings:
  • 19.4% of patients during the pandemic had a perforated appendix compared to 9.3% pre-pandemic (p = 0.045, OR = 2.46), indicating a significant increase in complications.
  • Overall appendectomy count decreased significantly during the pandemic (p < 0.001), suggesting reduced access to care.
  • The proportion of open appendectomies increased during the lockdown, reflecting changes in surgical practice.
Interpretation:

The COVID-19 lockdown was associated with a higher incidence of complicated appendicitis and a decrease in overall appendectomy cases, suggesting delayed patient presentations possibly due to fear of seeking care and a reduction in milder cases.

Limitations:
  • Single-center study may limit generalizability.
  • Retrospective design may introduce selection bias.
  • Impact of the pandemic on patient behavior and healthcare access may not be fully captured.
Conclusion:

The COVID-19 lockdown led to increased rates of perforated appendicitis and changes in surgical approaches, underscoring the critical importance of timely medical care to prevent complications.

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