To report a case of recurrent IgG4-related hypertrophic pachymeningitis (IgG4-RHP) and evaluate treatment outcomes, including symptom improvement and imaging results.
Key Findings:
Significant improvement in clinical symptoms after 6 months of combined therapy, including specific symptom resolution.
MRI scans showed resolution of the lesion and normalization of serum IgG4 levels, indicating effective treatment.
Steroid therapy is first-line; immunomodulatory agents are necessary for recurrent cases, highlighting the need for a tailored approach.
Interpretation:
IgG4-RHP should be considered in differential diagnoses for epidural masses; combined steroid and immunomodulatory therapy is effective for recurrence, potentially offering better outcomes than steroid therapy alone.
Limitations:
Single case study limits generalizability and may introduce biases.
Long-term outcomes and optimal treatment protocols remain unclear, necessitating further research.
Conclusion:
The case highlights the importance of surgical intervention and combined medical therapy in managing recurrent IgG4-RHP.
