Incidence and risk factors of post-transplant diabetes mellitus after kidney transplantation: a systematic review and meta-analysis - Summary - MDSpire
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Incidence and risk factors of post-transplant diabetes mellitus after kidney transplantation: a systematic review and meta-analysis
To investigate the incidence rate of post-transplant diabetes mellitus (PTDM) and identify its risk factors.
Key Findings:
Overall incidence of PTDM was 20%.
Significant risk factors include advanced age (>50), HCV infection, polycystic kidney disease, high BMI, high fasting plasma glucose, hypertriglyceridemia, and hypercholesterolemia.
Meta-analysis confirmed advanced age (OR = 1.07), high BMI (OR = 1.23), and hypertriglyceridemia (OR = 1.01) as significant risk factors.
Interpretation:
Limitations:
Heterogeneity in studies regarding diagnostic criteria and follow-up duration.
Variability in patient characteristics and statistical methodologies.
