Case Report: A case of diffuse subretinal fibrosis and uveitis syndrome with vitreoretinal traction syndrome - Summary - MDSpire

Case Report: A case of diffuse subretinal fibrosis and uveitis syndrome with vitreoretinal traction syndrome

  • By

  • Xiaohua Zhang

  • Yongping Hu

  • Jian Li

  • May 7, 2026

Share

Objective:

To document a case of diffuse subretinal fibrosis and uveitis syndrome occurring alongside vitreoretinal traction syndrome in an older female patient, highlighting the 4-year gap between symptom onset in each eye.

Key Findings:
  • The patient exhibited a 4-year gap between the onset of symptoms in each eye.
  • Bilateral SFU syndrome was complicated by VRT syndrome and retinal neovascularization.
  • Anti-VEGF therapy provided a partial therapeutic response for macular edema, highlighting the need for tailored management.
Interpretation:

SFU syndrome is a rare inflammatory condition with a complex clinical presentation and challenging treatment options, emphasizing the need for careful diagnosis and individualized management strategies.

Limitations:
  • Limited clinical accounts and evidence-driven treatment strategies for SFU syndrome, highlighting the need for more comprehensive case reports.
  • Inconsistent clinical trajectories and absence of uniform management protocols, which complicate treatment outcomes.
Conclusion:

SFU syndrome is uncommon and can present with significant complications. Treatment may delay subretinal fibrosis progression, and anti-VEGF therapy can help manage associated macular edema, underscoring the importance of tailored approaches in future cases.

Original Source(s)

Related Content