Hidden blood loss after proximal femur fractures fixation: analysis of the first three postoperative days and influence of anticoagulants - Summary - MDSpire

Hidden blood loss after proximal femur fractures fixation: analysis of the first three postoperative days and influence of anticoagulants

  • By

  • Jorge Mayor

  • Marcel Winkelmann

  • Lea-Sophie Schwinn

  • Hür Özbek

  • Gökmen Aktas

  • Tarek Omar-Pacha

  • Swantje Oberthür

  • Rike-Herta Krammig

  • Axel Gänsslen

  • Stephan Sehmisch

  • Jan-Dierk Clausen

  • May 16, 2026

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Objective:

To investigate the influence of specific anticoagulant therapies on perioperative blood loss, particularly hidden blood loss (HBL), in patients with proximal femur fractures.

Key Findings:
  • 260 patients were included, with a mean age of 81.2 years and 29.2% on anticoagulant therapy. Note: 293 patients were initially analyzed.
Interpretation:

The study highlights the significant impact of anticoagulant therapy on hidden blood loss in elderly patients undergoing surgery for proximal femur fractures, suggesting a need for careful perioperative management.

Limitations:
  • Retrospective design may introduce selection bias, potentially affecting the reliability of the findings.
  • Single-center study limits generalizability of findings to broader populations.
  • Potential confounding factors not fully controlled in analysis may skew results.
Conclusion:

Understanding the role of anticoagulant therapy in hidden blood loss is crucial for optimizing surgical outcomes in elderly patients with proximal femur fractures, emphasizing the need for tailored perioperative management strategies.

Original Source(s)

Hidden blood loss after proximal femur fractures fixation: analysis of the first three postoperative days and influence of anticoagulants

  • by Jorge Mayor, Marcel Winkelmann, Lea-Sophie Schwinn, Hür Özbek, Gökmen Aktas, Tarek Omar-Pacha, Swantje Oberthür, Rike-Herta Krammig, Axel Gänsslen, Stephan Sehmisch, Jan-Dierk Clausen

  • May 16, 2026

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