To investigate the association between bullying victimization, state gender-identity policy environments, and psychotic-like experiences among gender-diverse youths, specifically focusing on those assigned female at birth.
Key Findings:
Mean psychotic-like experience score was 7.5 for the most gender-diverse youths compared to 2.0 for the least gender-diverse.
Bullying victimization scores were 4.6 for the most gender-diverse compared to 2.8 for the least.
The most gender-diverse group scored 0.78 standard deviations higher on psychotic-like experiences than the least gender-diverse group.
Longitudinal analyses indicated that psychotic-like experiences increased over time among the most gender-diverse youths in low-support policy environments.
Interpretation:
The study suggests that bullying victimization and unsupportive state policies contribute to higher psychotic-like experiences in gender-diverse youths, highlighting the need for targeted mental health assessments and interventions.
Limitations:
Observational study design limits causal conclusions.
Participants excluded due to incomplete data may differ significantly from the broader cohort.
The policy metric reflects overall legislative climate rather than individual laws.
Potential biases in self-reporting may affect the accuracy of psychotic-like experience assessments.
Conclusion:
The findings emphasize the importance of considering social and political environments in the mental health care of gender-diverse youths, particularly in shaping supportive policies.
Genetically predicted urinary metabolite levels were associated with schizophrenia, bipolar disorder, attention-deficit/hyperactivity disorder, and anorexia nervosa in a Mendelian randomization analysis.