Not All Poststroke Cognitive Patterns Plateau - Summary - MDSpire

Not All Poststroke Cognitive Patterns Plateau

  • By

  • Kathryn Wighton

  • May 29, 2026

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Objective:

To investigate the evolution of cognitive impairment following stroke over time and identify recovery trajectories across different cognitive domains.

Key Findings:
  • Cognitive impairment improved most within the first 6 months but continued to evolve during long-term follow-up.
  • Acute cognitive impairment severity was the strongest predictor of long-term cognitive outcomes.
  • Recovery trajectories varied significantly across cognitive domains: greatest improvement in memory and language, limited improvement in attention and executive function.
  • Four global cognitive trajectories were identified: stable mild/no impairment, moderate acute impairment with improvement, severe acute impairment with large improvement, and moderate acute impairment followed by decline.
Interpretation:

Limitations:
  • Substantial attrition over time.
  • Lack of prestroke cognitive data.
  • Possible underrepresentation of patients with more severe stroke due to the need for concentration during assessments.
  • Long-term testing was performed remotely due to COVID-19 disruptions.
Conclusion:

Original Source(s)

Not All Poststroke Cognitive Patterns Plateau

  • by Kathryn Wighton

  • May 29, 2026

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