Molecular and cellular adaptations to extended hypothermic oxygenated perfusion in donation-after-circulatory-death hearts in a porcine model - Summary - MDSpire

Molecular and cellular adaptations to extended hypothermic oxygenated perfusion in donation-after-circulatory-death hearts in a porcine model

  • By

  • Morgan K. Moroi

  • Yaagnik Kosuri

  • Cary Karcher

  • Diana Albino

  • Anthony Campbell

  • Arianna Adamo

  • Emre Bektik

  • Christine Chan

  • Kenmond Fung

  • Miroslav Sekulic

  • Shaheer K. Faruqi

  • Craig J. Goergen

  • Melissa Tamimi

  • Koji Takeda

  • Giovanni Ferrari

  • May 25, 2026

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Objective:

Consider adding the significance of the findings in the context of heart transplantation.

Key Findings:
  • Include implications of each finding for clinical practice.
Interpretation:

Link findings back to the broader context of DCD heart transplantation.

Limitations:
  • Expand on potential biases or confounding factors in the study design.
Conclusion:

Emphasize the potential impact of HOPE on future DCD heart transplantation practices.

Original Source(s)

Molecular and cellular adaptations to extended hypothermic oxygenated perfusion in donation-after-circulatory-death hearts in a porcine model

  • by Morgan K. Moroi, Yaagnik Kosuri, Cary Karcher, Diana Albino, Anthony Campbell, Arianna Adamo, Emre Bektik, Christine Chan, Kenmond Fung, Miroslav Sekulic, Shaheer K. Faruqi, Craig J. Goergen, Melissa Tamimi, Koji Takeda, Giovanni Ferrari

  • May 25, 2026

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