Optical coherence tomography acquisition efficiency: comparison of Heidelberg spectralis OCT2 module & Zeiss Cirrus HD-OCT model 6000 - Summary - MDSpire

Efficiency of Optical Coherence Tomography Acquisition: A Comparative Study of Heidelberg SPECTRALIS OCT2 and Zeiss CIRRUS HD-OCT 6000

  • By

  • Charissa H. Tan

  • Michael S. Jensen

  • Shannon Fitch

  • Richard Ordonez

  • Abigail Jacketta

  • Jeff Courtright

  • Jonathan Shepherd

  • Mathew Vierkant

  • Paul Crown

  • Ben J. Brintz

  • Susan Chortkoff

  • Brian C. Stagg

  • July 20, 2026

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Objective:

To compare optical coherence tomography (OCT) acquisition times between the Heidelberg SPECTRALIS OCT2® module and Zeiss CIRRUS™ HD-OCT Model 6000 in a glaucoma clinic setting.

Approach:
  • Method: Study Design
  • Method: Imaging Protocol
  • Method: Data Collection
Key Findings:
  • Cirrus 6000 had a total scan time of 115.9 ± 44.7 seconds, significantly faster than Spectralis OCT2 at 157 ± 46.4 seconds (p < 0.001).
  • RNFL acquisition times were shorter with Cirrus 6000 (50.8 ± 29.7 seconds) compared to Spectralis OCT2 (99.5 ± 32.7 seconds; p < 0.001).
  • Macular scan times did not show significant differences (p = 0.180).
  • Spectralis OCT2 achieved higher completion rates and required fewer repeat attempts.
Interpretation:

Cirrus 6000 offers meaningful time savings for RNFL imaging, potentially improving workflow efficiency in high-volume glaucoma clinics, while Spectralis OCT2 demonstrated greater reliability in challenging imaging conditions.

Limitations:
  • Different scoring scales for image quality precluded direct cross-device comparison.
  • Study limited to a specific patient population at a single institution.
Conclusion:

Device selection should be individualized based on patient characteristics, clinic workflow, and imaging priorities, as there is no single superior platform.

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