Relationships between anxiety–depression, perceived social support, and in-hospital outcomes among patients with acute myocardial infarction - Summary - MDSpire

Relationships between anxiety–depression, perceived social support, and in-hospital outcomes among patients with acute myocardial infarction

  • By

  • Yuemei Zhu

  • Xiao Zhu

  • Yingying Zhou

  • June 16, 2026

  • 0 min

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Objective:

To examine associations between early anxiety–depression symptoms, perceived social support, and in-hospital outcomes in patients with acute myocardial infarction (AMI).

Key Findings:
  • 44.0% of patients exhibited clinically significant anxiety–depression symptoms (HADS ≥11).
  • 27.3% of patients developed at least one complication during hospitalization.
  • Higher HADS scores were associated with increased risk of complications, prolonged hospital stay, and poorer sleep quality (all P < 0.05).
  • Higher PSSS scores were associated with reduced complication risk, shorter hospital stays, and improved sleep quality (all P < 0.05).
  • Psychosocial risk stratification showed a significant gradient across all outcomes (trend P < 0.05).
Interpretation:

Early anxiety–depression symptoms and perceived social support are associated with in-hospital outcomes in AMI patients.

Limitations:
  • Single-center study may limit generalizability.
  • Cross-sectional design does not allow for causal inferences.
  • No follow-up beyond hospitalization was performed.
Conclusion:

Routine psychosocial screening may help identify high-risk patients.

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