Case Report: Preoperative treatment of portal hypertension by splenic artery embolization for safe major hepatectomy: experience in three patients - Summary - MDSpire

Case Report: Preoperative treatment of portal hypertension by splenic artery embolization for safe major hepatectomy: experience in three patients

  • By

  • Duygu Gürel

  • Tevfik Güzelbey

  • Oğuzhan Aydın

  • Serhat Kaya

  • Özgür Bostancı

  • İlgin Özden

  • March 25, 2026

  • 0 min

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Objective:

To evaluate the effectiveness of preoperative splenic artery embolization (SAE) in alleviating portal hypertension in patients undergoing major hepatectomy.

Key Findings:
  • SAE led to normalization of platelet counts within two weeks for all patients.
  • Regression of esophageal varices was observed post-SAE.
  • All patients successfully underwent major hepatectomy with varying degrees of future remnant liver volumes.
Interpretation:

SAE is a viable preoperative intervention for managing portal hypertension in patients with liver tumors, potentially improving surgical outcomes and reducing the risk of post-hepatectomy liver failure.

Limitations:
  • Small sample size limits generalizability.
  • Lack of long-term follow-up data for all patients.
Conclusion:

SAE should be considered for portal flow modulation in major hepatectomy candidates with portal hypertension, as it can enhance surgical safety and outcomes.

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