A hybrid implementation-effectiveness study of a school-based intervention for promoting health and well-being in low-resource settings: the ISOBAR study protocol - Summary - MDSpire

A hybrid implementation-effectiveness study of a school-based intervention for promoting health and well-being in low-resource settings: the ISOBAR study protocol

  • By

  • Swaran P. Singh

  • Catherine Winsper

  • Nadia Binte Alam

  • Tolulope Bella-Awusah

  • Graeme Currie

  • Oluwabunmi (Tokun) Fola-Bolumole

  • Domenico Giacco

  • Paramjit Gill

  • Sanjana Goutham

  • Srividya N. Iyer

  • Jasmine Kalha

  • Isha Lohumi

  • Jason Madan

  • Dafne Moroni

  • Olayinka Omigbodun

  • Soumitra Pathare

  • Shiva Prakash Srinivasan

  • Simon Smith

  • J.S. Thakur

  • Thara Rangaswamy

  • Helena Tuomainen

  • Samuel Watson

  • Sagar Jilka

  • July 14, 2026

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Objective:

To develop, implement, and test a school-based intervention addressing mental and physical health problems in low-and-middle-income countries (LMICs).

Approach:
  • Intervention Phases: The ISOBAR project consists of three phases: pre-intervention (co-development and cultural adaptation), implementation, and post-intervention evaluation.
  • Target Population: The intervention will be delivered to 1,800 adolescents across nine schools in Chennai, Gujarat (India), and Ibadan (Nigeria).
  • Assessment Methods: Assessments will evaluate intervention effectiveness, implementation processes, and cost-effectiveness.
Key Findings:
  • The intervention is culturally adapted to each study region.
  • Development and delivery are grounded in co-production.
  • The study aims to build research capacity in LMICs, particularly in implementation science and health economic evaluation.
Interpretation:

Causal inference may be limited due to the absence of a randomized controlled trial and ethical considerations that provide guidance to control condition students.

Limitations:
  • Logistical and ethical constraints prevent a randomized controlled trial.
  • Control condition students receiving guidance may dilute the intervention's effect.
Conclusion:

The ISOBAR project aims to address the dual burden of mental and physical health issues among adolescents in LMICs through a culturally adapted school-based intervention.

Original Source(s)

A hybrid implementation-effectiveness study of a school-based intervention for promoting health and well-being in low-resource settings: the ISOBAR study protocol

  • by Swaran P. Singh, Catherine Winsper, Nadia Binte Alam, Tolulope Bella-Awusah, Graeme Currie, Oluwabunmi (Tokun) Fola-Bolumole, Domenico Giacco, Paramjit Gill, Sanjana Goutham, Srividya N. Iyer, Jasmine Kalha, Isha Lohumi, Jason Madan, Dafne Moroni, Olayinka Omigbodun, Soumitra Pathare, Shiva Prakash Srinivasan, Simon Smith, J.S. Thakur, Thara Rangaswamy, Helena Tuomainen, Samuel Watson, Sagar Jilka

  • July 14, 2026

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