Individualized treatment for pediatric intracranial aneurysms in China: case series and literature review - Summary - MDSpire

Individualized treatment for pediatric intracranial aneurysms in China: case series and literature review

  • By

  • Guohong Song

  • Haihui Jia

  • He Tong

  • Hua Xu

  • Changyi Hu

  • Bo Li

  • Hao Chen

  • June 11, 2026

  • 0 min

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Objective:

To analyze the clinical presentation, treatment selection, and outcomes of pediatric patients with ruptured intracranial aneurysms.

Approach:
    Key Findings:
    • All four patients successfully underwent treatment, with three showing neurological improvement.
    • One patient with severe preoperative brain herniation died postoperatively.
    • A total of 27 pediatric intracranial aneurysm cases were analyzed, with a male-to-female ratio of 16:11.
    • Common symptoms included sudden severe headache, nausea, vomiting, and impaired consciousness.
    • Endovascular embolization was performed in 11 cases, microsurgical clipping in 10 cases, and combined surgery in 1 case.
    Interpretation:

    Ruptured pediatric intracranial aneurysms present with nonspecific symptoms, necessitating accurate diagnosis through multimodal imaging. Treatment strategies should be individualized based on clinical presentation and patient-specific factors.

    Limitations:
    • Small sample size and retrospective nature of the study limit the generalizability of findings.
    • Lack of large-scale, long-term follow-up data on pediatric intracranial aneurysms hinders understanding of outcomes.
    Conclusion:

    Individualized treatment approaches are essential for managing pediatric intracranial aneurysms, with a focus on precise diagnosis and tailored therapeutic strategies.

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