Success of femtosecond laser-assisted deep anterior lamellar keratoplasty (Femto-DALK): a clinical case series of 42 eyes using an intraoperative optical coherence tomography (iOCT)-guided laser-generated pre-descemet tunnel - Summary - MDSpire
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Clinical Outcomes of Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty: An iOCT-Guided Pre-Descemet Tunnel Case Series of 42 Eyes

  • By

  • Nicola R. Otto

  • Friedrich A. Steindor

  • Gerd Geerling

  • Theo G. Seiler

  • October 14, 2026

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Objective:

To report real-world outcomes of femtosecond laser-assisted DALK using an iOCT-guided pre-Descemet intrastromal tunnel.

Approach:
  • Design and setting: Retrospective single-center case series of all patients undergoing Femto-DALK from January 2020 through December 2023; one surgeon performed all procedures.
  • Procedure: A Ziemer LDV Z8 laser and integrated iOCT were used to plan the lamellar plane and create a tunnel ending approximately 30 μm anterior to DM. Air was injected through the tunnel to attempt Big-Bubble formation; manual stromal dissection was used if it failed.
  • Data collected: Records were reviewed for surgical indications, Big-Bubble formation, DM perforation, conversion to PK, operative duration, and postoperative outcomes.
Key Findings:
  • The supplied context describes the study design and surgical technique but does not provide the results for the 42 eyes.
Interpretation:

The supplied excerpt describes a retrospective, single-center case series of Femto-DALK performed by one surgeon from January 2020 through December 2023. It does not include study results or follow-up outcomes.

Limitations:
  • Retrospective, single-center study.
  • All procedures were performed by one surgeon.
  • The supplied context does not include the study’s results or follow-up outcomes.
Sources:

Original Source(s)

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