Optimizing Exercise Interventions for Pain Relief in Breast Cancer Survivors: A Systematic Review and Dose-Response Network Meta-Analysis - Summary - MDSpire
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Optimizing Exercise Interventions for Pain Relief in Breast Cancer Survivors: A Systematic Review and Dose-Response Network Meta-Analysis

  • By

  • Hao Huang

  • Xueying Chen

  • Zhibo Wang

  • Yifan Zhang

  • December 6, 2025

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Objective:

To identify the most effective exercise modalities and doses for pain management in breast cancer survivors, thereby improving their quality of life, through a dose-response network meta-analysis.

Approach:
    Key Findings:
    • Approximately 42% of breast cancer survivors experience chronic pain.
    • Exercise has minimal side effects and can promote the release of analgesic substances.
    • Existing meta-analyses lack clear exercise prescriptions for pain management.
    Interpretation:

    The findings suggest that tailored exercise prescriptions could effectively manage pain in breast cancer survivors, addressing a significant gap in current clinical practice.

    Limitations:
    • The analysis may be limited by the variability in exercise modalities and dosages across studies.
    • Potential publication bias and the exclusion of non-RCTs may affect the comprehensiveness of the findings.
    Conclusion:

    Developing evidence-based exercise prescriptions for pain management in breast cancer survivors is crucial for improving clinical outcomes.

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