Unveiling the Rare Coexistence: Thyroid Hemiagenesis and Thyroid Cancer - Case series and Comprehensive Review - Summary - MDSpire

Unveiling the Rare Coexistence: Thyroid Hemiagenesis and Thyroid Cancer - Case series and Comprehensive Review

  • By

  • Guiming, Fu

  • Zhou, Hongxia

  • Wan, Ting

  • Li, Yinfeng

  • Wang, Zhaohui

  • Hou, Yanjia

  • May 4, 2026

  • 0 min

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Objective:

To analyze the occurrence and management of thyroid hemiagenesis (THA) complicated by thyroid carcinoma (TC).

Key Findings:
  • 32 instances of THA complicated by TC identified, predominantly in females (27 out of 32).
  • Papillary thyroid carcinoma (PTC) accounted for 81.3% of cases.
  • 29 patients underwent surgical intervention, with various diagnostic imaging techniques utilized, including color Doppler ultrasonography, CT imaging, and fine-needle aspiration biopsy.
Interpretation:

The coexistence of THA and TC is rare, potentially linked to genetic factors; diagnostic methods are similar to those for typical TC, underscoring the need for awareness in clinical practice.

Limitations:
  • Lack of comprehensive data on incidence and etiology.
  • No evaluations of surgical complications and long-term outcomes, highlighting a gap in current research.
Conclusion:

Surgical resection remains the primary treatment, with the extent of resection debated; clinical guidelines for conventional TC should guide surgical approaches, and further research is needed on long-term outcomes.

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