Objective:

To determine the seroprevalence of HBV and HCV co-infections among PLHIV receiving ART in the Upper East Region of Ghana and assess the extent of liver injury in this population.

Approach:

Key Findings:

• High seroprevalence of HBV (15.6%) and HCV (8.4%) among PLHIV in the Upper East Region.
• Co-infections complicate ART management and increase liver injury risk.
• Routine screening for HBV and HCV co-infections is not universally implemented.

Interpretation:

The findings highlight the significant burden of HBV and HCV co-infections among PLHIV in Ghana, necessitating improved screening and management strategies.

Limitations:

• Cross-sectional design limits causal inference.
• Potential selection bias in participant recruitment.

Conclusion:

The study underscores the need for routine screening and tailored ART regimens to manage co-infections and reduce liver-related morbidity in PLHIV.

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