Objective:

To determine the seroprevalence of HBV and HCV co-infections among PLHIV receiving ART in the Upper East Region of Ghana and assess the extent of liver injury in this population.

Approach:

Key Findings:

• High seroprevalence of HBV (15.6%) and HCV (8.4%) among PLHIV in the Upper East Region.
• Co-infections complicate ART management and increase liver injury risk.
• Routine screening for HBV and HCV co-infections is not universally implemented.

Interpretation:

The findings highlight the significant burden of HBV and HCV co-infections among PLHIV in Ghana, necessitating improved screening and management strategies.

Limitations:

• Cross-sectional design limits causal inference.
• Potential selection bias in participant recruitment.

Conclusion:

The study underscores the need for routine screening and tailored ART regimens to manage co-infections and reduce liver-related morbidity in PLHIV.

Source

Based on findings from:

Assessment of the occurrence and factors influencing hepatitis B, hepatitis C, and liver damage in individuals with HIV undergoing antiretroviral treatment in Ghana's Upper East Region

Francis Yennube Duut, Samuel Punignan Nfoke, Elvis Ayamga, Naja Kwayaja, Dodzi Kwaku Jnr Senoo, Godfred Agongo, James Abugri, Sylvester Donne Dassah. Bmc Infectious Diseases, 2026.

https://link.springer.com/article/10.1186/s12879-026-12784-y

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