Digital tools and biomarkers for cognitive screening: A systematic review - Summary - MDSpire

Digital tools and biomarkers for cognitive screening: A systematic review

  • By

  • Seunghui Hong

  • ChanHee Kim

  • Seon Heui Lee

  • June 22, 2026

  • 0 min

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Objective:

To synthesize and contrast traditional neuropsychological tests, digital cognitive assessment tools, and digital biomarkers for cognitive evaluation.

Approach:
    Key Findings:
    • Traditional neuropsychological tests are time-consuming and require trained personnel.
    • Digital cognitive assessment tools enhance accessibility and scalability.
    • Digital biomarkers capture subtle cognitive changes through real-world interactions.
    • AI-driven multimodal biomarkers show higher sensitivity for early Alzheimer’s detection.
    Interpretation:

    Digital cognitive assessments and biomarkers show promise for enhancing early detection and monitoring of cognitive decline, but practical feasibility in community settings needs further evaluation.

    Limitations:
    • Discrepancies in scores between digital and traditional tests.
    • Variability in digital literacy among older adults.
    • Lack of standardized scoring frameworks.
    Conclusion:

    Community nurses can enhance accessibility to digital cognitive assessments, but face operational challenges that need addressing.

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