Indirect cognitive mapping in glioma surgery in patients not eligible for awake craniotomy – how I do it - Summary - MDSpire

Indirect cognitive mapping in glioma surgery in patients not eligible for awake craniotomy – how I do it

  • By

  • Patrick Vigren

  • Hans Lindehammar

  • November 7, 2025

  • 0 min

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Objective:

To describe a technique for preserving cognitive function during glioma surgery in patients who are not eligible for awake craniotomy due to specific clinical or anatomical factors.

Key Findings:
  • Intraoperative mapping can preserve cognitive functions even when awake craniotomy is not feasible, which is critical for patient quality of life.
  • Electrical stimulation parameters can effectively localize motor pathways and protect adjacent cognitive structures, ensuring better surgical outcomes.
  • All three cases resulted in successful tumor resections without new neurological deficits, demonstrating the technique's effectiveness.
Interpretation:

The described technique offers a viable alternative for glioma surgery in patients unable to undergo awake procedures, ensuring the preservation of cognitive functions.

Limitations:
  • The technique may not be applicable to all patients due to varying anatomical and clinical factors, such as tumor location and patient tolerance.
  • Brain shift during large tumor resections can complicate neuronavigation accuracy, potentially impacting surgical outcomes.
Conclusion:

Indirect cognitive mapping is a promising approach for glioma surgery, allowing for the safe resection of tumors while minimizing the risk of cognitive deficits.

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