To identify independent predictive factors for atrial fibrillation detected after stroke (AFDAS) and to investigate its association with recurrent ischemic stroke.
Approach:
Study Design: Secondary analysis of data from the prospective, multicenter China National Stroke Registry II (CNSR-II).
Definition of AFDAS: AFDAS was defined as a new atrial fibrillation episode (> 30 s) detected after the onset of acute ischemic stroke (AIS).
Data Analysis: Multivariable logistic regression was used to identify risk factors linked to AFDAS and to explore the relationship between AFDAS and ischemic stroke recurrence.
Key Findings:
Among 23,446 patients, 572 (2.4%) developed AFDAS.
Independent risk factors for AFDAS included older age (≥ 65 years: OR = 2.14, 95% CI: 1.44–3.16), history of coronary arterial disease (OR = 1.88, 95% CI: 1.22–2.92), elevated C-reactive protein (OR = 1.02, 95% CI: 1.01–1.02), and lower triglyceride levels (OR = 0.76, 95% CI: 0.61–0.96).
The recurrence rate of stroke was significantly higher in the AFDAS group (11.7%) compared to the sinus rhythm group (6.1%).
AFDAS remained an independent risk factor for 1-year stroke recurrence after adjusting for traditional risk factors (OR = 1.82, P < 0.001).
Interpretation:
Limitations:
The study is based on a secondary analysis of registry data, which may have inherent biases.
The findings may not be generalizable to populations outside of the study cohort.
