Early warning scores for predicting in-hospital mortality in patients with acute aortic dissection - Summary - MDSpire

Early warning scores for predicting in-hospital mortality in patients with acute aortic dissection

  • By

  • Mao Hu

  • Nan Xie

  • Lvna Xiang

  • July 13, 2026

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Objective:

To evaluate the prognostic value of early warning score (EWS) in predicting in-hospital mortality among patients with acute aortic dissection (AAD).

Approach:
  • Study Design: Retrospective analysis of consecutive AAD patients presenting to the emergency department in 2022.
  • Data Collection: Collected demographic information, clinical characteristics, EWS, laboratory findings, and time to computed tomography angiography (CTA).
  • Statistical Analysis: Performed univariable and multivariable logistic regression analyses to identify risk factors for in-hospital mortality.
Key Findings:
  • NEWS demonstrated the highest discriminative performance among the three EWS with an AUC of 0.581 (95% CI 0.528–0.634).
Interpretation:

NEWS may serve as a tool for initial risk stratification in patients with AAD, although its overall predictive ability is modest.

Limitations:
  • Retrospective design may introduce selection bias.
  • Data limited to a single institution may affect generalizability.
Conclusion:

Type A AAD and surgical treatment were the only independent predictors of in-hospital mortality.

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