To investigate the differences in two-dimensional speckle tracking echocardiography (2D-STE) parameters among patients with different types of acute decompensated heart failure (ADHF) and their correlation with left ventricular ejection fraction (LVEF).
Approach:
Study Design: Cross-sectional investigation involving 98 patients hospitalized due to ADHF, categorized into HFrEF and HFpEF subgroups based on LVEF.
Echocardiography: All patients underwent transthoracic echocardiography and 2D-STE to assess myocardial strain parameters.
Key Findings:
HFpEF group showed significantly higher absolute values of GLSA4C, GLSA2C, GLSA3C, LV-GLS, LASR-ED, LASRD-ED, LASRT-ED, RVFWSL, and RV4CSL compared to HFrEF (P < 0.05).
HFrEF subgroup had higher LAFI and LASI values compared to HFpEF (P < 0.05).
In HFrEF, LVEF negatively correlated with GLSA4C, GLSA2C, GLSA3C, LV-GLS, RVFWSL, RV4CSL, LASr-ED, LASrct-ED, LAFI, and LASI (P < 0.05).
In HFpEF, LVEF negatively correlated only with GLSA4C, GLSA2C, GLSA3C, and LV-GLS (P < 0.05).
After controlling for LVEF, LV-GLS remained correlated with LASr-ED, LASrcd-ED, and LASrct-ED in both heart failure groups (P < 0.05).
Interpretation:
The study reveals significant differences in 2D-STE parameters between HFrEF and HFpEF, with varying correlations of LVEF with these parameters across the subtypes.
Limitations:
The HFmrEF subgroup was too small for robust statistical analysis.
The study's cross-sectional design limits causal inferences.
Conclusion:
The findings indicate differences in 2D-STE parameters between HFrEF and HFpEF patients.
