The impact of the SARS-CoV-2 pandemic on umbilical cord blood transplantation in Japan: insights from an interrupted time series analysis - Summary - MDSpire

The impact of the SARS-CoV-2 pandemic on umbilical cord blood transplantation in Japan: insights from an interrupted time series analysis

  • By

  • Nobuhiko Nakamura

  • Tetsuji Morishita

  • Hiromi Hayashi

  • Motohito Okabe

  • Hideki Nakasone

  • Naoyuki Uchida

  • Noriko Doki

  • Takahiro Fukuda

  • Satoshi Yoshihara

  • Masatsugu Tanaka

  • Tetsuya Nishida

  • Yuta Hasegawa

  • Ken-ichi Matsuoka

  • Masashi Sawa

  • Tetsuya Eto

  • Makoto Onizuka

  • Yuta Katayama

  • Koji Kato

  • Fumihiko Ishimaru

  • Ken Tabuchi

  • Yoshiko Atsuta

  • Nobuhiro Kanemura

  • Takanori Teshima

  • April 17, 2025

  • 0 min

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Objective:

To explore the impact of COVID-19 on the choice of cord blood transplantation (CBT) in Japan, highlighting its significance during the pandemic.

Key Findings:
  • HSCT activities in Japan remained stable during the pandemic, unlike declines reported in other regions, indicating a unique resilience.
  • Cord blood transplantation (CBT) was effectively utilized as an alternative donor source during the pandemic, showcasing its critical role.
  • The number of HSCT cases before the pandemic was 33,170, and after was 7,274, reflecting a significant drop that warrants further investigation.
Interpretation:

The stability of HSCT activities in Japan during the pandemic may be attributed to the effective use of CBT, highlighting its importance as a readily available donor source in emergencies and suggesting potential strategies for future crises.

Limitations:
  • The study is retrospective and relies on registry data, which may have inherent biases, particularly in reporting and data collection.
  • Findings are specific to Japan and may not be generalizable to other countries, necessitating caution in applying these results elsewhere.
Conclusion:

The study underscores the resilience of Japan's HSCT system during the COVID-19 pandemic, particularly through the use of umbilical cord blood as a critical resource, suggesting that similar strategies could be beneficial in other contexts.

Original Source(s)

The impact of the SARS-CoV-2 pandemic on umbilical cord blood transplantation in Japan: insights from an interrupted time series analysis

  • by Nobuhiko Nakamura, Tetsuji Morishita, Hiromi Hayashi, Motohito Okabe, Hideki Nakasone, Naoyuki Uchida, Noriko Doki, Takahiro Fukuda, Satoshi Yoshihara, Masatsugu Tanaka, Tetsuya Nishida, Yuta Hasegawa, Ken-ichi Matsuoka, Masashi Sawa, Tetsuya Eto, Makoto Onizuka, Yuta Katayama, Koji Kato, Fumihiko Ishimaru, Ken Tabuchi, Yoshiko Atsuta, Nobuhiro Kanemura, Takanori Teshima

  • April 17, 2025

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