Correlation of ABO/Rh Blood Types with Transfusion-Related Infections in Turkish Blood Donors: An In-Depth Demographic Study (2015–2021) - Summary - MDSpire

Correlation of ABO/Rh Blood Types with Transfusion-Related Infections in Turkish Blood Donors: An In-Depth Demographic Study (2015–2021)

  • By

  • Aziz Karaca

  • Özgür Rüştü Güner

  • Mustafa Nuri Günçıkan

  • Mustafa Yılmaz

  • Gizem Gökçe Karadağ

  • Nazlı Nadire Sözmen

  • Levent Sağdur

  • Kerem Kınık

  • Fatma Meriç Yılmaz

  • February 13, 2026

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Objective:

To assess the prevalence trends of transfusion-transmitted infections (TTIs) such as HIV, HBV, HCV, and syphilis among Turkish blood donors from 2015 to 2021, identify demographic risk factors, and evaluate the association between ABO/Rh blood groups and TTI risks.

Approach:
    Key Findings:
    • TTIs remain a public health concern in Türkiye, with varying prevalence across different demographics.
    • ABO/Rh blood groups may influence susceptibility to TTIs, but findings are inconsistent across studies.
    • Demographic factors such as age and education level are significant in assessing TTI risk, particularly among younger donors.
    Interpretation:

    The study highlights the need for further research on the relationship between blood groups and TTIs, considering demographic factors, to inform targeted blood safety measures.

    Limitations:
    • Retrospective design may introduce bias.
    • Data limited to Turkish blood donors, affecting generalizability.
    • Potential confounding factors not fully accounted for in the analysis.
    Conclusion:

    The study emphasizes the importance of understanding demographic and genetic factors in TTI risk to improve blood safety measures.

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