Worldwide Rates and Determinants of Depression and Anxiety Among Individuals with Liver Cirrhosis: A Systematic Review and Meta-Analysis - Summary - MDSpire
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Worldwide Rates and Determinants of Depression and Anxiety Among Individuals with Liver Cirrhosis: A Systematic Review and Meta-Analysis
To synthesize global prevalence estimates of depression and anxiety among patients with liver cirrhosis, along with associated risk factors and geographic distribution.
Key Findings:
Pooled prevalence of depression among cirrhotic patients was 0.37 (95% C.I. 0.29–0.46).
Pooled prevalence of anxiety among cirrhotic patients was 0.53 (95% C.I. 0.33–0.73).
Age, alcoholism, and viral etiologies were linked to increased depression incidence.
Interpretation:
Depression and anxiety significantly impair the quality of life in patients with liver cirrhosis, yet their diagnosis is often overlooked.
Limitations:
High heterogeneity in prevalence estimates across studies.
Limited number of studies from certain geographic regions.
Conclusion:
Standardizing screening for depression and anxiety in cirrhosis patients can enhance their treatment outcomes and quality of life.
This quality improvement project found that using a distress screening tool for head and neck cancer patients who were 2 or more years post-treatment led to an increased number of referrals for psychosocial needs.
