Risk prediction models for peristomal moisture-associated skin damage in China: a systematic review and meta-analysis - Summary - MDSpire

Risk prediction models for peristomal moisture-associated skin damage in China: a systematic review and meta-analysis

  • By

  • Haijia Liu

  • Mengzhen Huang

  • Yuanfan Yang

  • Fen Zhao

  • Huilin Long

  • Bo Huang

  • June 4, 2026

  • 0 min

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Objective:

To systematically identify and critically evaluate currently available risk prediction models for Peristomal Moisture-Associated Skin Damage (PMASD), highlighting the significance of PMASD in patient care.

Key Findings:
  • A total of 11 prediction models from 10 studies were included, with an incidence rate of PMASD ranging from 22.8% to 59.1%.
  • All studies indicated a substantial risk of bias, limiting their clinical utility.
  • The area under the curve (AUC) values of the models ranged from 0.812 to 0.914.
  • Strongest predictors identified included history of radiotherapy, type of stoma, stoma opening height, and surgical wound in the plate area.
  • Three studies validated the model externally, and six studies used a combination of internal and external validation methods, while one study did not validate the model.
Interpretation:

Although most models showed good applicability, they all exhibited inherent limitations due to high risk of bias, which may affect their clinical implementation.

Limitations:
  • High risk of bias in all included studies, which may compromise the reliability of the findings.
  • Limited external validation of the models, raising questions about their generalizability.
  • Variability in the incidence rates reported across studies, which could impact the interpretation of model performance.
Conclusion:

Future large-sample, multicenter, and high-quality prospective clinical studies are needed to optimize predictive models for PMASD, addressing the identified limitations to enhance their clinical application.

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