Automated segmentation of pituitary adenomas, pituitary gland, and internal carotid arteries on routine coronal contrast-enhanced T1-weighted MRI: a single-sequence feasibility study - Summary - MDSpire

Automated segmentation of pituitary adenomas, pituitary gland, and internal carotid arteries on routine coronal contrast-enhanced T1-weighted MRI: a single-sequence feasibility study

  • By

  • Woojae Hong

  • Ho Kang

  • Jong Ha Hwang

  • Seong-Min Kim

  • Yong Hwy Kim

  • Hyunggun Kim

  • June 30, 2026

  • 0 min

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Objective:

To evaluate the feasibility and clinical relevance of Swin-Unet and nnU-Net for automated segmentation of pituitary adenomas, pituitary gland, and internal carotid arteries using contrast-enhanced T1-weighted coronal MRI.

Approach:
  • Performance Metrics: Model performance was assessed using the Dice similarity coefficient (DSC), 95th percentile Hausdorff distance (HD95), true-positive rate (TPR), and false-positive rate (FPR).
Key Findings:
  • Mean Dice similarity coefficient was 0.70 (95% CI: 0.66-0.74) for Swin-Unet and 0.69 (95% CI: 0.65-0.73) for nnU-Net.
  • Mean Hausdorff distance was 5.21 mm (95% CI: 4.40-6.03) for Swin-Unet and 5.30 mm (95% CI: 4.44-6.16) for nnU-Net.
Interpretation:

Automated segmentation of pituitary adenomas, pituitary gland, and internal carotid arteries using single-sequence T1CE coronal MRI is feasible, with moderate voxel-level accuracy and reliable slice-level recognition.

Limitations:
  • Segmentation accuracy was lower for the pituitary gland.
  • Performance may decline when applied to heterogeneous imaging data.
Conclusion:

The study indicates the potential utility of automated segmentation as an adjunct tool for radiologic assessment and surgical planning.

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