Post-surgical outcomes in transgender women: a prospective analysis of sexual function and health-related quality of life - Summary - MDSpire

Post-surgical outcomes in transgender women: a prospective analysis of sexual function and health-related quality of life

  • By

  • M. J. Wenk

  • N. Rademacher

  • B. Liedl

  • B. Grüne

  • B. Meister

  • September 2, 2025

  • 0 min

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Objective:

To prospectively evaluate specific patient-reported outcome measures (PROMs) related to sexual function and health-related quality of life (QOL) in transgender women before and after gender-affirming surgery.

Key Findings:
  • The study aims to provide robust data on surgical outcomes, QOL, and sexual function in transgender women post-GAS, highlighting significant improvements.
  • Existing literature shows limited evidence on the improvement of sexual function post-GAS, underscoring the need for more prospective data.
Interpretation:

The study seeks to fill gaps in current research by providing longitudinal data on sexual function and QOL in transgender women after surgery, crucial for understanding the effectiveness of gender-affirming treatments.

Limitations:
  • The study may be limited by the lack of validated questionnaires specifically for sexual function in transgender individuals, potentially affecting the reliability of the findings.
  • Potential biases in self-reported data and the observational nature of the study may influence the results.
Conclusion:

This study aims to enhance understanding of the impact of gender-affirming surgery on sexual function and health-related quality of life in transgender women, contributing valuable insights to clinical practice.

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